11/11/2024
research article
Unique mtDNA variants in a controlled nuclear background reveal how mtDNA influences immune efficiency and identify a protective variant against diverse pathogens.
Image credit: pgen.1011476
Current Issue December 2024
11/14/2024
research article
Advancing our understanding of the diversity of phototransduction in nematodes even in the absence of eyes.
Image credit: pgen.1011320
11/12/2024
research article
PPIP5K, PFA-DSP and NUDT inositol pyrophosphate phosphatases regulate growth and development by collectively shaping plant PP-InsP pools.
Image credit: pgen.1011468
11/07/2024
research article
p21 and ROS cooperate in FA cells to induce replication abnormalities, linking p21 accumulation with S-phase defects and genetic instability.
Image credit: pgen.1011474
11/07/2024
research article
Sequencing confirmed transgene excision by SSA in ~4% of progeny, with wild-type alleles and mutations indicating limited maternal Cas9 RNP deposition, highlighting ReMEDE's potential as a gene drive mitigation strategy.
Image credit: pgen.1011450
11/11/2024
research article
MVMR with dependent, as opposed to independent, sets of instrumental variables significantly expands the scope for predicting causal genes in disease risk loci with pleiotropic regulatory effects.
Image credit: pgen.1011473
09/11/2024
research article
A SNP at MEF2C (rs6893807), linked to IQ, ...
Image credit: pgen.1011093
09/12/2024
research article
Ancestral sequence reconstruction and analyses of natural and chimeric variants identified six key amino acids involved in sensor-helper compatibility.
Image credit: pgen.1011402
09/11/2024
research article
Using an evolutionary method that examines proteins that evolve at similar rates, the authors identified proteins within glycosylation pathways ...
Image credit: pgen.1011406
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PLOS Genetics welcomes several new Associate Editors to our board: Nicolas Bierne, Julie Simpson, Yun Li, Hongbin Ji, Hongbing Zhang, Bertrand Servin, & Benjamin Schwessinger
The former Natural Variation section at PLOS Genetics relaunches as Human Genetic Variation and Disease. Read the editors' reasoning behind this change.
Quanjiang Ji (ShanghaiTech University) joined the editorial board and Xiaofeng Zhu (Case Western Reserve University) was promoted as new Section Editors for the PLOS Genetics Methods section.
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